Posted: December 29th, 2012 | Author: M.Aaron Silverman | Filed under: Applied Science, Cankler Science News, Chemically Engineered, Engineered Life, Health, Medicated | Tags: Breast Cancer, Cancer, Cancer Research, ELF5 Protien, Garvin Institute, Protein-to-protein Interaction, RNA, Therapeutic Options | Comments Off on Garvin Institute Discover Critical Breast Cancer Protien
Australian researchers have discovered a key factor explaining the lack of effectiveness of some breast cancer treatments. Associate Professor Chris Ormandy from Sydney’s Garvan Institute says a protein he has been studying for a decade plays a critical role in the development of breast cancer.
The researchers have shown how a ‘transcription factor’ causes breast cancer to develop an aggressive subtype that lacks sensitivity to oestrogen and does not respond to anti-oestrogen therapies such as Tamoxifen and aromatase inhibitors.
Transcription factors are molecules that switch genes on or off. In this case, the transcription factor known as ‘ELF5’ inhibits sensitivity to oestrogen very early in the life of a breast cancer cell :: Read the full article »»»»
Posted: February 14th, 2012 | Author: Verity Penfold | Filed under: Cankler Science News, Medicated | Tags: Aspirin, Cancer Research, Clinical Oncology, Non-steroidal Anti-inflammatories, NSAID, Peter MacCallum Cancer Institute | Comments Off on Australian Scientists Probe Aspirins Role in Cancer Treatment
Researchers from Melbourne’s Peter MacCallum Cancer Institute – PMCI – say they have made an important discovery about how cancer spreads. A 2010 article published in the Journal of Clinical Oncology has previously suggested that aspirin may reduce the risk of death from breast cancer. While the information has been well-circulated by the media, official health bodies and medical groups have expressed concern over the touting of aspirin as a “miracle drug”
Scientists have known for years that common drugs like aspirin can help cancer patients, but they weren’t sure why. PMCI researchers have now found a link between drugs like aspirin and the ability for cancer tumours to spread in the body. Read the full article »»»»