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The Rise and Rise of Allergies! Microbial Deprivation and Hygiene Hypothesis

Posted: August 29th, 2012 | Author: | Filed under: Cankler Science News, Health, Medicated, Wiki | Tags: , , , , , , , , , | Comments Off on The Rise and Rise of Allergies! Microbial Deprivation and Hygiene Hypothesis

The Rise and Rise of Allergies, Microbial Deprivation - The Hygiene Hypothesis - Diverse Human Gut FloraI consider myself a germaphobe, the thought of unseen creepy crawlies does serious damage to my mind, bleach is my best friend.

I’ve fallen in love with antibacterial wipes, vinegar, indeed anything that will KILL microbes on surfaces anyplace near me. I grow a huge smile every time I see Asian tourists strolling the streets in surgical face masks, are we overreacting?

It turns out I might be overreacting, scientists reckon that some germs are good? I must point out that Hygiene – as used in this post –  has little relationship with ‘hygiene’ in the usual meaning of the word. The term ‘hygiene hypothesis’ is unfortunate, as it is misleading. A better term would be Microbial Deprivation Hypothesis.

Our immune systems are our single most important line of defense against infection.

The bacteria and germs that surround us, some of these microbes can be nasty, really nasty, causing food poisoning, colds, a variety of other infections as well as diseases.

It is perhaps the ones inside that we need worry most about though, many researchers are now focusing on dysfunctional colonies of microbes within human beings for causes to disorders such as asthma, MS and autism, including disorders previously believed to be entirely brain based like epilepsy, depression and even my favourite, Bipolar Disorder.

I must warn, this is an opinion piece, it is based on several hypotesis – of others – a little thought, possibly some hyperbole and a little wishful thinking, it is meant entirely for thought provocation :: Read the full article »»»»


Wiki! PROTOSCIENCE

Posted: January 12th, 2012 | Author: | Filed under: Wiki | Tags: , , , | Comments Off on Wiki! PROTOSCIENCE

ALBERTProtoscience or Proto-science: In the philosophy of science, a protoscience is a new science trying to establish its legitimacy. Protoscience is distinguished from pseudoscience by its standard practices of good science, such as a willingness to be disproven by new evidence, or to be replaced by a more predictive theory.

Compare fringe science, which is considered highly speculative or even strongly refuted. Some protosciences go on to become an accepted part of mainstream science.

All sciences would have qualified as protosciences before the Age of Enlightenment, since the scientific method still hadn’t been developed, and there was no structured way to prove legitimacy.

A standard example is alchemy, which from the 18th century became chemistry, or pre-modern astrology which from the 17th century became astronomy :: Read the full article »»»»


Wiki! Force

Posted: August 15th, 2011 | Author: | Filed under: Wiki | Tags: , , , , | Comments Off on Wiki! Force

In physics, force is what changes or tends to change a state of rest or motion in an object. Force causes objects to accelerate, add to the object’s overall pressure, change direction, or change shape. Force is measured in Newtons. (‘N’).

According to Newton’s Second Law of Motion, the formula for finding force is:

'''F = ma'''

where F is the force,
m is the mass of an object,
and a is the acceleration of the object.

If one sets a to the standard gravity g, then another formula can be found:

'''W = mg'''

where W is the weight of an object,
m is the mass of an object,
and g is the acceleration due to gravity at sea level.

at  about 9.8m/s^2.

Force is a vector, so it has both a magnitude and a direction.

Another equation that is useful is:

F=G(m1)(m2)/d^2

F is forceG is the gravitational constant, which is used to show how gravity accelarates an object; m1 is the mass of one object; m2 is the mass of the second object; and d^2 is the distance between the objects.

A force is always a push, pull, or a twist, and it affects objects by pushing them up, pulling them down, pushing them to a side, or by changing their motion or shape in some other way.


Wiki! GOUT

Posted: June 11th, 2011 | Author: | Filed under: Wiki | Tags: , , , , , , , , | Comments Off on Wiki! GOUT

GOUTGout, also known as podagra when it involves the big toe, is a medical condition usually characterized by recurrent attacks of acute inflammatory arthritis, a red, tender, hot, swollen joint. The metatarsal-phalangeal joint at the base of the big toe is the most commonly affected (approximately 50per cent of cases).

However, it may also present as tophi, kidney stones, or urate nephropathy. It is caused by elevated levels of uric acid in the blood which crystallize, and the crystals are deposited in joints, tendons, and surrounding tissues.

A clinical diagnosis is confirmed by the visualization of the characteristic crystals in joint fluid. Treatment with nonsteroidal anti-inflammatory drugs, steroids, or colchicine improves symptoms.

Once the acute attack has subsided, levels of uric acid are usually lowered via lifestyle changes, and in those with frequent attacks, allopurinol or probenecid provide long-term prevention.

Gout has increased in frequency in recent decades, affecting about 2 per cent of the western population at some point in their lives. The increase is believed to be due to increasing risk factors in the population, such as metabolic syndrome, longer life expectancyand changes in diet. Gout was historically known as “the disease of kings” or “rich man’s disease” :: Read the full article »»»»


Wiki! ASPIRIN

Posted: January 11th, 2011 | Author: | Filed under: Wiki | Tags: , , , , , , , , | Comments Off on Wiki! ASPIRIN

ASPIRINAspirinacetylsalicylic acid, is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatorymedication. Aspirin was first isolated by Felix Hoffmann, a chemist with the German drug company Bayer, under the direction of Arthur Eichengrün.

Salicylic acid, the main metabolite of aspirin, is an integral part of human and animal metabolism. While in humans much of it is attributable to diet, a substantial part is synthesized endogenously.

Aspirin also has an antiplatelet effect by inhibiting the production of thromboxane, which under normal circumstances binds platelet molecules together to create a patch over damaged walls of blood vessels. Because the platelet patch can become too large and also block blood flow, locally and downstream, aspirin is also used long-term, at low doses, to help prevent heart attacks, strokes, and blood clot formation.

It has been well established that low doses of aspirin may be given immediately after a heart attack to reduce the risk of another heart attack or of the death of cardiac tissue. Some people take a daily aspirin to reduce their risk of heart attack. New evidence suggests aspirin may be a powerful tool in cancer prevention, as well.

The main undesirable side effects of aspirin taken by mouth are gastrointestinal ulcers, stomach bleeding, and tinnitus, especially in higher doses. In children and adolescents, aspirin is no longer indicated to control flu-like symptoms or the symptoms of chickenpox or other viral illnesses, because of the risk of Reye’s syndrome :: Read the full article »»»»