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Breakthrough Cancer Treatment Improves Survival Rates

Posted: April 22nd, 2013 | Author: | Filed under: Medicated | Tags: , , , , , , , | Comments Off on Breakthrough Cancer Treatment Improves Survival Rates

Peter MacCullum Cancer InstituteResearchers in Melbourne have used a new targeted treatment technique to achieve the highest-ever long-term survival rates for patients with some forms of lung cancer.

The team from Peter MacCallum Cancer Institute used PET/CT – Positron Emission Tomography / Computed Tomography – scans to determine the location and stage of tumours in 76 patients with locally advanced non-small cell lung cancer.

The patients were treated with a combination of radical radiation therapy and chemotherapy, leading to a four year survival rate of 32 per cent, the highest ever published.

Research team leader, Associate Professor Michael MacManus, says that is dramatically higher than the historic average of between 10 and 20 per cent.

PET/CT scanning uses a device which combines both PET and an x-ray Computed Tomography, so that the produced images – taken by both devices sequentially – combine into a single superposed image, a 3D map. The image shows the spatial distribution of metabolic activity in the body can be more precisely ::::

PET-CT Siemens

“We were really gobsmacked and delighted that the survival was so good,” Professor MacManus said. “We’re very much ahead of the game in respect to this. We’re very pleased that our public hospital patients in Melbourne are receiving treatment that’s produced results that are in fact better than anything reported so far in the world in this group of patients.”

PET-CT has revolutionized many fields of medical diagnosis, by adding precision of anatomic localisation to functional imaging, which was previously lacking from pure PET imaging. One obstacle to a wider use of PET-CT has been the difficulty and cost of producing and transporting the radio-pharmaceuticals used for PET imaging, which are usually extremely short-lived, for instance, the half life of radioactive fluorine18 used to trace glucose metabolism is two hours only. Its production requires a very expensive cyclotron as well as a production line for the radio-pharmaceuticals.

Lung Cancer remains one of the most incedeous and preventable forms of cancer. The main types of lung cancer are small-cell lung carcinoma – SCLC – and non-small-cell lung carcinoma – NSCLC. The most common cause of lung cancer iremains long-term exposure to tobacco smoke, which causes 90 per cent of lung cancers. Non-smokers account for 10 per cent of lung cancer cases, these cases are often attributed to a combination of genetic factors, radon gas, asbestos,  air pollution – including second-hand tobacco smoke. If your still smoking and need assistance to get of the drug, checkout the QUIT NOW website: www.quitnow.gov.au

Professor MacManus says the scanning method also helped identify which patients should be spared unnecessary treatment. The results of the study will be published in the journal Radiation and Oncology.

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source: petermac
source: elsevier
source: abc
source: wikipedia

Detailed Lung Cancer Treatment:source: cancervic

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